Comments by "" (@DanielSMatthews) on "America's coronavirus response 'completely uncoordinated'" video.

  1. Because I had to tell the silly buggers how to save their sorry asses?
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  2. The White House now know about the following technology, so let us see if they are smart & agile enough to implement it in time to make a difference. The COVID-19 virus is, in abstraction, just a finite automata propagating through a substrate and that substrate is humanity, most mitigation efforts center around futile attempts to partition off parts of the substrate, other more effective but risky strategies involve modifying the behavior of the substrate to make it hostile to the virus. Great work guys but you got lost in the details and missed something very obvious. Make humanity just a small part of the substrate and make most of it incapable of replicating the virus. So how can we do that? Genetically engineer a lactobacillus bacteria that is ubiquitous in the environment and on human mucosa so that the bacteria expresses the ACE2 (or any other required viral target!) gene so that the virus attempts to merge with the bacteria as if it was a human cell. The bacteria will however be engineered to immediately destroy the conserved parts of the viral genome. You can make the organism safer by also making it dependent on an artificial amino acid that does not exist in nature. This lets you brew up a self replicating and sustaining, yet controllable, bioshield that can cover surfaces in buildings, public spaces and on the bodies of humans including the areas that are targeted by the virus, the mucosa.
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