Comments by "TJ Marx" (@tjmarx) on "Omicron: What we know so far about the new COVID-19 variant | DW News" video.
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@tipsy Bass @ tipsy bass Wow, what a ridiculous lot of disjointed terms thrown together in the most absurd way. Ad hom straight off the bat followed by literal nonsense.
Your sentence structure, forming and information are all atrocious.
My original comment was just a series of factual corrections not a jab at you. I've been in medicine for 17 years, have epidemiology experience, public health education including correction of mistakes in comments is literally a part of job.
Could I have put in more effort to the original comment, sure but really those corrections should be enough for you to bother to investigate further or clarify with me.
You're online mate, you have access to the collective knowledge of all of humanity and you didn't even bother to look up what you're talking about before you replied. Instead you let your insecurity at being corrected force you into the rambling mess you call a comment. Let me guess, you're still in high school.
Here's a new set of corrections for you;
The changes do not take place in a host cell. The changes are physiological changes to the spike proteins on the virus itself. These physiological changes bring new characteristics to a virus and how in engages both with host cells and the immune system of the host.
Contrary to your claim, an electron microscope does not view things at the *cellular level*. A standard optical microscope is very capable of doing that. I'm sure everyone here at least remembers viewing onion or plant cells under an entry level high school optical microscope in grade 7 - 9, depending on the country they live in.
An electron microscope, as the name suggests, uses electrons (electricity as opposed to the light used in optical) to bombard a sample and form a image at the particle level.
We are not looking at omicron under electron microscopy to determine changes to its protein structure. 🤣🤣
We use genome sequencing. In a report, sequencing displays DNA pairs, or RNA typically as lines or letters which correspond to proteins in the structure. Sequencing to 100 pairs was completed when SA reported Omicron (B.1.1.529). I have a copy of the sequencing for omicron sitting on my desk.
Viral load is not a term which describes a cell exploding. Viral load is simply the term used to describe the amount of virus in a host. One needs a big enough initial viral load in order for a virus to successfully replicate. Limiting the ability for a significant enough viral load to be acquired is how social distancing and eradication through vaccination (colloquially so called "herd immunity") works.
Apoptosis (you didn't even spell it correctly) is preprogrammed cellular death. That is to say, it's a condition where a cell dies purposefully. It is a mechanism by which your body controls cellular growth, division and discards unhealthy or unwanted cells. Where apoptosis fails, we see tumour growth. That is to say failed apoptosis is a primary factor in many cancers.
Some viruses absolutely do hijack apoptosis by various mechanisms to replicate, however that is in no way specific to omicron and is not indicative of the changes present.
The way HIV hijacks apoptosis is very different to the way coronaviruses do.
I'm sorry that your uncle has HIV, but that does not excuse your distribution of misinformation. You acknowledge that you're not an expert, so perhaps instead of jumping to conclusions through insecurity in the future you might consider that a stranger correcting you might be an expert as in this case, and enquire further.
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