Comments by "Dorchester Mom" (@DorchesterMom) on "What is the Origin and Reason for Green Eyes?" video.

  1. Green eyed lady here - can confirm four living generations in a straight matrilineal line from my Nana down to my daughter (H6a1b2) have them. They are my favorite physical attribute ❤ I’m an American, but my autosomal DNA is entirely Northern European. Mostly Irish but also Scots and English. My Nana’s matrilineal line goes back to Blackburn, England but possibly Ireland prior to that. My maternal haplogroup was found in a sample among an Yamnayan burial site, which is so interesting to me. Thank you for making this video, I learned a few new things!
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  2. I was just poking around my promethease report looking for SNPs and found I have an allele associated with a higher likelihood for a type of green eyes in European populations. It’s associated with glutamine on the OCA2 receptor. Anyways, I know many other factors come into play, but this was interesting! rs1800407(A;G) green/hazel/brown/black eyes more likely rs1800407 is located in exon 13 of the OCA2 gene at amino acid position 419, and it is therefore also known as the R419Q variant. The (A) allele encodes the amino acid glutamine (instead of arginine), and it is associated with increased odds of having green/hazel eye color in some Caucasian populations. One copy of of rs1800407(A) is sufficient for this effect.
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