Comments by "Goose" (@goose7574) on "Gupta stunned by Trump-Fauci difference at briefing" video.

  1. 2-3 days? WOW! Someone has A LOT of wax in their ears if you heard that.
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  2. Once again CNN is so freaking biased and doesn't show what the guy from the FDA said, and soooo much more. You guys, watch the actual briefing... PLEASE! People in SEATTLE...*RIGHT NOW* are taking certain meds that they are trying for COVID19
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  3.  @IsomSeales  You aren't understanding what's going on. Oh well... Your loss!
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  4.  @IsomSeales  Here, read this and educate yourself a bit! Stop relying on Fake news. "Malaria is a disease that is caused by a parasite, unlike COVID-19. Nevertheless, laboratory studies show chloroquine is effective at preventing as well as treating the viruse that causes severe acute respiratory syndrome, or SARS, a close cousin of COVID-19." THIS is why they believe it might work!!!
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  5.  @IsomSeales  Here's a bit more info for the You do you can understand the reasoning behind it. The science behind chloroquine First developed in the 1940s, chloroquine earned FDA approval as a malaria treatment in 1949 and long stood as the go-to treatment for the disease, according to the DrugBank database. A 2005 report published in the journal Virology first raised the possibility that chloroquine and its derivative hydroxychloroquine might be effective at treating COVID-19, Dr. Len Horovitz, an internist and pulmonary specialist at Lenox Hill Hospital in New York City, told Live Science. The study revealed that chloroquine could prevent the spread of the SARS-CoV virus, which caused severe acute respiratory syndrome nearly 20 years ago, in primate cells grown in culture. Chloroquine interferes with the virus's ability to replicate in two ways. First, the drug enters compartments called endosomes within the cell membrane. Endosomes tend to be slightly acidic, but the chemical structure of the drug boosts their pH, making the compartments more basic. Many viruses, including SARS-CoV, acidify endosomes in order to breach the cell membrane, release their genetic material and begin replication; chloroquine blocks this critical step. The drug also prevents SARS-CoV from plugging into a receptor called angiotensin-converting enzyme 2, or ACE2, on primate cells, according to the 2005 report. When the virus inserts its spike protein into the ACE2 receptor, it sets off a chemical process that alters the structure of the receptor and allows the virus to infect. An adequate dose of chloroquine appears to undermine this process, and in turn, viral replication in general, the authors noted. "It was thought that whatever pertained to SAR-CoV-1 might apply to SARS-CoV-2," Horovitz said. Hope that helps you understand things more!
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