Comments by "Vierotchka" (@Vierotchka) on "Dr. John Campbell" channel.

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  17. Here is what ZDoggMD says about REGEN-Cov-2: He got Regeneron’s monoclonal antibody cocktail. What is a monoclonal antibody and what does it do? So let me see if I can explain this simply. You’ve heard of convalescent plasma. Convalescent plasma is a fraction of the blood that’s removed from patients who’ve recovered from COVID-19. Presumably it contains antibodies that the patient has made against the corona SARS coronavirus 2. And by infusing it into a patient with active coronavirus disease, you presume that those antibodies will bind to the virus and help your immune response to contain the viral replication. Now what’s the downside of convalescent plasma? It has a mix of all kinds of stuff. So it has antibodies that don’t necessarily neutralize the virus, but they may bind to the virus and in some cases, that can actually enhance viral uptake. I’m not saying that’s what happens with SARS-CoV-2, but it does happen with things like Dengue. It’s so-called antibody mediated enhancement. So when you don’t bind to the right part of the virus, you can actually cause the virus to be recognized and pulled into the very cells it’s trying to infect. Now again, we don’t know that that occurs with SARS-CoV-2, but it’s certainly a risk and the data on convalescent plasma is still pretty soft. We’re waiting on really good prospective randomized control trials to see. And it’s not without risk because because of the other components you can have allergic reactions and that sort of thing, kind of similar to a transfusion reaction, right? But what did the president get? The president got monoclonal antibodies. These are designed to bind to the actual business end of the virus, the spike protein on the capsule of the virus that’s responsible for binding to human cells and bringing it into the cell. Those are neutralizing antibodies and what that means, and I’d encourage you to watch the interview I did with Paul Offit where we went through this, there’s a couple on my website, ZDoggMD.com. What that means is that the virus is actually knocked out by antibodies binding to it, by the immune response that’s triggered by that and so on. And they neutralize the virus. Now there’s a couple different antibodies there so that different variants, I won’t use the technical terms of the virus that might escape the initial antibodies might have less chance of that with multiple binging antibodies. Now what’s the status of this drug, right? It’s very expensive, it’s very hard to make, it’s very hard to scale up and only 10 people including the president have gotten it outside of the current ongoing randomized control trials in humans under compassionate use. The president is one of them. So he got something very, very special that’s not part of a trial that he got very early on, I think Friday, when he was not well enough and they actually had to take him by helicopter to Walter Reed. By the way, very concerning. Anyone who tells you that’s not concerning, and oh there’s just an abundance of caution. Something was going on with the president that concerned the doctors enough that they wanted to take these actions and that’s fine. You wanna do that.
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  37. Health officials worry about long-term effects of COVID-19 on kids More than one-third of all kids tested for COVID-19 in the state are testing positive. It’s even higher in Lee County at 46%. Now, some health officials are sounding the alarm about the potential longer-term effects of this virus on our kids. Health experts say we still have a lot to learn. A warning from Doctor Alina Alonso, the director of the Department of Health Palm Beach County: Just because you don’t see any COVID-19 symptoms in a child doesn’t mean damage hasn’t been done. “And while many of these especially younger children are asymptomatic when you take x-rays of their lungs, down in Miami and other places across the country, they’re seeing that there is damage to the lungs in these asymptomatic children.” While Alonso says there’s proof asymptomatic children are suffering lung damage now, she and other warn we also need to start thinking about the lasting consequences these kids may have to live with. “We may have to deal with this virus for decades because of not just the survivors coming back with consequences, but also those who were the silent, infected individuals,” said Dr. Bindu Mayi, professor of microbiology at NSU’s College of Medical Sciences. On Thursday, when asked about the issue, Governor Ron DeSantis cited a lack of studies and evidence as a reason we shouldn’t be too concerned yet. "It would be irresponsible for me to say, ‘There will never be any long term’ because we just don’t know. But it’s also problematic to say in 20 years, there’s going to be all of these problems because we just don’t know that." Instead, the governor says we should stick to the proven facts, like focusing on the best strategy to avoid infection: wearing a mask and social distancing. Experts say one reason we know so little about the virus is because of how it spreads throughout the body. It can impact multiple organs and body systems in different ways in different people. https://www.winknews.com/2020/07/17/health-officials-worry-about-long-term-effects-of-covid-19-on-kids/
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  44. Golikova named the reasons for the increase in the incidence of COVID-19 in Russia The main reasons for the incidence of COVID-19 in Russia are participation in public events and non-observance of the mask regime. This was announced on September 29 by Deputy Prime Minister Tatyana Golikova at a meeting with President Vladimir Putin. “If we do not want the restrictions that we had in March-April - at the beginning of May this year, then we must strictly comply with all [sanitary] requirements,” Golikova said. She noted that the daily increase in the incidence of COVID-19 in Russia increased by 1.7 times - from 3.1 to 5.5 times per 100 thousand population. According to surveys, 80-85% of patients say that the reason is their non-observance of the mask regime and participation in mass events. “The rate of increase in the incidence in the country as a whole is kept at the level of 0.5-0.7%. <...> The spread of coronavirus infection, the so-called reproduction rate, is 1.1 in Russia today. This means that it has increased compared to the figure [which was recorded] three weeks ago. Today, only 41 regions have this figure below one, ”Golikova stressed. She also said that at the moment in Russia there are opportunities to increase the production of test kits to detect coronavirus infection. In addition, according to her, the free bed capacity for patients with COVID-19 is currently 31%. Earlier on the same day, Rospotrebnadzor said that the situation with the spread of coronavirus infection in Russia is under control, but depending on the number of new cases, new restrictions may be introduced. The day before, Putin said that the fight against the coronavirus was not over yet and that it was impossible to lose vigilance. According to him, the country ranks 40th in the world in terms of the number of cases per 100 thousand citizens, and in terms of the number of deaths - 100th place, writes Gazeta.ru. Source: https://iz.ru/1067024/2020-09-29/golikova-nazvala-prichiny-rosta-zabolevaemosti-covid-19-v-rossii
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