Comments by "Deborah Freedman" (@deborahfreedman333) on "Doctors baffled by Covid-19 'long hauler' patients" video.

  1. The public needs to wear masks, the president, a gag.
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  2. And this man was not high risk, no preexisting conditions and under 60, yet his health is totally shot. Sure, he survived, but he went from robust health to being a near invalid.
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  3. Not quite. The immune system has two components, cellular and humoral immunity. Humoral immunity is B cell production of antibodies, after being presented with the antigen by a T helper cell. Cellular immunity consists of macrophages, granulocytes, eosinophils, blast cells and T killer cells. They communicate with each other with cytokines. Many of the people who recovered with no symptoms have no antibody production, but their T killer cells are shown, in vitro, to destroy the virus. While most of the people who developed a lot of antibodies suffered terrible symptoms. I'll take a proper cellular response any day, over humoral response.
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  4.  Josh Edmonds  Chloroquine and hydroychloroquine act by raising the oxidative stress. They have no effect on the immune system, none. But, they can cause red blood cells to rupture.
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  5.  Josh Edmonds  Wow, so many lies. First, the virion doesn't have a receptor, but it does latch onto the ACE-2 receptor. That is how it enters a host cell. Second, for those with a weak immune response, it overwhelms the host and kills them. It enters the host cell, takes it over and kills it. If too many cells in the lungs are killed, you can't get enough oxygen and die. So it is not just the cellular immune response setting off a cytokine storm. Yes, that happens, but even without it, this virus can kill. And if you have excess adipose tissue, the inflammation is even worse, which is why it kills the obese more than the thin. And people who take ACE-2 inhibitors, for many heart conditions, develop more ACE-2 receptors on their cells. So, the virus has more routes to enter host cells. That is why those with heart conditions get sicker.
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  6. No, in an autoimmune disease the immune system attacks self cells. This is more like a really bad allergic reaction. The immune system on overdrive.
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