Comments by "Deborah Freedman" (@deborahfreedman333) on "'Tumors just vanished': Cancer patients now in remission after drug trial" video.

  1. Which antibody was your dog given? I doubt it was this one.
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  2. Another survivor here, who endured the trifecta of pain, chemo, surgery and radiation. I wish this less destructive treatment had been available.
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  3. The physicians answer was rather vague, so I looked this monoclonal up. It is anti-PD-1. PD-1 (programmed death) receptors, are found on T cells, and when activated, prevents the T cell sending tumor cells the signal to self destruct. Many tumor cells overexpress these ligands, that bind to these receptors, and turn off the T cell activity, that would kill the tumor cells. By removing these ligands, through anti-PD-1 antibodies, the T cells can kill the tumor cells. As breast cancer, gastric cancer, glioblastoma multiforme, NSCLC, and some hematologic malignancies, all produce these PD-1 ligands, this new MAb might work to treat them all. As a breast cancer survivor, who endured chemotherapy, I wish this MAb had been around ten years ago. It would have been a preferable treatment.
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