Comments by "Deborah Freedman" (@deborahfreedman333) on "New study finds popular zero-calorie sweetener linked to heart attack and stroke" video.
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It was published in Nature Medicine and called "The artificial sweetener erythritol and cardiovascular event risk". I just looked at it, and it seemed sketchy at best. It consists of two parts, an overall survey of people who consumed stevia, with a decent sample size, that showed a correlation between cardiac incidents and stevia consumption. They looked at people who had had heart attacks and strokes, and saw a good number consumed stevia. They did not see if healthy people also consumed stevia, and stayed healthy. They did one study with healthy people, but only 8 of them, and saw elevated erythritol levels somewhat correlated to higher platelet activity. But, a sample size of 8, where 5 people showed higher platelets, really isn't conclusive.
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Since I don't trust non-scientists to understand scientific studies, I looked for the paper, which was published in Nature. First, they saw a linkage between erythritol consumption and cardiac events, but did not demonstrate causality, just correlation. It would not be surprising if those who are overweight, both had more heart attacks, and tried to remedy that through use of non-nutrative sweeteners. There was some evidence, that higher erythritol blood levels also correlated to higher platelet activity. But, once again, it was just correlation, not proof of causation, and the sample size of that study was only eight individuals.
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