Comments by "Jake Johnson" (@ElectronFieldPulse) on "Drug-Dependent Infants Detox at Tenn. NICU" video.
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@c.a.greene8395 - I think I made my point poorly, as I agree with everything that you have said. Opioids do indeed have profound effects on the anatomical and physiological make up of the addict. And, as you mentioned without saying the word, epigenetics is involved which causes future children to be at risk for many different malignancies. I have a bachelors in biochemistry, and I used to listen to a lot of different professors, including ones who studied fentanyl. Interested fact, fentanyl binds so strongly to the mu opioid receptor that it actually pulls the receptor protein out of the the cell membrane. This is why tolerance sky rockets so quick with it.
All this to say, my question was if opioids aurally are sequestered into every cell type in the body. After perusing through the blood, being metabolized by the liver, and excreted, I would imagine there are some systems which might evade having an opioid influx, lymphocytes perhaps? So lymph nodes? I honestly don't know, I've been out of school for 15 years and I work as a chemist now, so I was genuinely asking. I wasn't minimizing the dangers of opoids, I agree with you.
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