Comments by "Ginny Jolly" (@ginnyjollykidd) on "Почему важно знать группу крови? — Натали Ходж" video.

  1. XoletteScience I have always found blood typing a popular class subject. Your explanation is mostly right, white cells ignore red cells of the self. But I think how they do it is fuzzy. Macrophage can't ignore invaders, so it seems to me they have to recognize red cells as self. To do that, I think there must be a probing of proteins. Consider that a macrophage might attach to a red cell's ABO proteins and then release them if they are self cells. I don't know the exact mechanism of self - recognition. If you have a journal article that speaks to this, please let me know the reference. Thank you.
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  2. Xolette I like the idea of using viruses created to invade cancer cells. I've thought about this, too.
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  3. Wrong! The ABO and Rh antigens are NOT the only antigens, though they are the main ones. There are I, J, K, M, N, T and several more antigens and antibodies to test, and the typing analysis results look like a crossword puzzle when finished. But that's not enough. Because there might be some antigen we don't know about, recipient blood is cross - matched with donor blood. The string of packets of blood hanging from a blood unit are used to mix with recipient blood to see if it clumps. If it does, an unknown antigen is present that can endanger a patient. If no clumping occurs, the unit is safe to use. And how are antibodies treated in a unit of whole blood? These might cause problems, too. A whole blood unit is separated into plasma and red cells. The red cells become a unit I of "Packed Cells" with added citrate to prevent clotting. Plasma contains the white cells and are removed with the plasma to keep from attacking a recipient. Alternatively, people are encouraged to give platelets for people with hemophilia or bleeding disorder. It takes ten donations to create a unit of platelets or enough for creating blood clotting factor.
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