Comments by "Steven Goldstein" (@stevengoldstein114) on "Jordan Peterson - Depression Is a Positive Feedback Loop" video.

  1. Jordan misrepresents the way depression works, here is information from a true medical resource. The Queensland Brain Institute states: But what triggers the stress response in the first place? The major activating input comes from the amygdala, a part of the brain important for the processing of emotions, particularly negative emotions. Thus when someone experiences negative emotions, the amygdala becomes more active, which can trigger the stress response in the HPA axis. The released glucocorticoids then trigger a positive feedback loop with the amygdala and NEGATIVE feedback loops with the hippocampus and prefrontal cortex (Figure 1). If the balance of excitation from the amygdala and inhibition from the hippocampus and prefrontal cortex favours HPA activation (amygdala excitation > hippocampus, prefrontal cortex inhibition), positive feedback occurs and chronic stress and depression can result. Chronic stress produces excess levels of glucocorticoids, which can lead to the death of neurons, particularly in the hippocampus. This may be relevant to the mode of action of the most commonly prescribed antidepressant drugs, SSRIs (selective serotonin reuptake inhibitors; see below). He is not being medically accurate here
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