Comments by "Banana" (@439bananas) on "Chubbyemu"
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@gillenzfluff8380 Well I frankly can not understand the pricing structure on medical cannabis. I believe that there is a company that makes medical grade in the UK, it is a licensed facility as you can imagine. It is really only a matter of growing, harvesting when in flower and extracting the drug, in fact, it was available on the NHS as hemp tincture until 1972. As for the mega expensive drugs, they are frequently monoclonal antibodies, there are 2 ways to make them, either through hybridoma lines I know this to be an expensive and time consuming method or phage display, I have no idea about this method.
They are posited to work by searching out tumour cells by locking onto surface molecules that are unique to that cancer. However, one of the problems is penetration into the centre of the tumour is often not good. When tumours get big they grow their own network of blood vessels, but the problem is that when they get big, chunks of the cancer split off and set up in other parts of the body (metastasis). I personally think that the best approach might be to develop a multistage treatment. So start out with a suitable monoclonal whilst surgical excision is being arranged. Remove the tumour and as soon as the patient is well enough start administering the monoclonal again and then zap any remaining tumour with radiotherapy. Zapping it right away seems to make tumours impervious to monoclonals.
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