Comments by "Stephen Villano" (@spvillano) on "Heme Review" channel.

Went through similar, with increasing hypertension that was presumed to be age and familial related. Right until things decompensated and I dropped 30+ pounds in a month and had a hypertensive crisis. Whoopsie! Missed Grave's disease, TSH receptors getting lit up by antibodies, sending my thyroid gland into overdrive. A couple of thyroid storms later, it was mischief managed. Now, just for entertainment's sake, my immune system did something not unusual in Grave's disease, it switched to destruction mode and I'm moving into Hashimoto's. Not unexpected, given my eldest grandchild has it.
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@akshinbarathi8914 the problem with cancer cells is, they "forgot" how to die when their genome gets partially scrambled and worse, ignore both cellular signaling for when to grow or stop reproducing and signals that tell them where to live within the body. So, cells that ignore signals that tell them that they're malfunctioning and should die are ignored, the cells reproduce out of control and cells that, as an example, should be part of one's skin end up growing wherever the bloodstream and lymphatic system carries them. And Henrietta Lacks cervical cancer cells are still growing today, despite her dying from her cancer in 1951 and are some of the cells used to test chemotherapy drugs worldwide today.
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I had a heat stroke while in the Persian Gulf region in 2009. Broken AC in the car (no air conditioned showrooms at the repair shop, so I figured I'd wait for it to cool down before getting it fixed), dehydrated slightly secondary to having a few drinks the evening before, got stuck in traffic on the way to the base and I had for once, forgotten to bring a few bottles of water to work with me. Got to the base and was already beginning to experience a heat stroke. Base security delays in the sun made it a bit worse. I managed to get plenty of water into me at the MP station, as initially everyone thought I was inebriated and as I downed my 6th bottle of water, it dawned on the MP's what was actually going on. I recovered, minor cardiac damage with a slightly funky QT interval and sent the ECG analyzer into fits claiming digitalis effect, throw PVC's moderately often after and throw a bit of protein in the urine. Amazingly, my liver didn't show any damage whatsoever!
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@DavidBentley23 actually, dimenhydrinate is an antihistamine related to diphenhydramine, with dimenhydrinate most commonly used as an antinausea medication for motion sickness and diphenhydramine being most commonly used as a histamine blocker. From there, it gets rather complicated, as both also interact with other receptors and a video runs the risk of turning into an advanced pharmacology course. Still, if doctor can Goober it down, I'm sure it'd be worthwhile.
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Instant alkaline water... CsOH, perhaps? Never forget, folks, Libertarians tell us that we don't need the FDA, as business and the free market would nip it in the bud. You know, ignore radium and thorium water and well, history.
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@samiraperi467 or Master of Public Health, but the former is a tad more entertaining if there wasn't a major public health emergency in progress.
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Caffeine withdrawal, aka, migraine from hell - literally. Only, it's a global one, rather than just one or two blood vessels involved. Yeah, been there, done that, although I don't get the nausea with caffeine withdrawal, just the headache and fuzzy feeling, muddled thinking, etc. Thanks to COVID damage (mitral valve regurgitation and some conduction issues), I had to cut way down on my coffee. Literally going from a full 12 cup pot of coffee per day to 3 cups per day, otherwise I ended up throwing enough PVC's to toy with v-tach. That took about a year to finally largely resolve, although the valve leak is one that isn't going to resolve. I'll be getting signed up for a full body transplant soon, my only problem is that they keep trying to pawn off one with a brain in it. ;)
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I'm aware of only one field where what otherwise would be considered subtherapeutic dosing is common - pain management that utilizes what's more typically utilized as a general anesthetic. This is, of course, physician guided and managed, administered by a physician and monitored by a physician for specific physiological goals. And I recall that this was discussed in professional pain management conferences that I'd attended back in the mid-2000's and today is of a moderately effective management program for certain specified chronic pain instances. I did work with one cyanide containing food product for my dinner - cassava root. But, unlike wild cassava, aka bitter cassava - a famine food, this was cultivated root. The biggest risk wasn't cyanide poisoning, but of slicing and dicing my fingers. Did get one modest cut, so shallow it didn't even bleed, but annoyingly is over an index finger joint. What I get for careless handling of knives that I maintain as literal scalpel edge sharpness. And boy, was that cassava root (aka yuca root) good in my chicken stew! With some mixed veggies, cowpeas and kidney beans, plus my favored barley and a small handful of noodles. Got 3 quarts remaining in the fridge, with some home made bread awaiting another few meals. And I actually do know how to prepare the wild cassava, learned that while deployed in areas where it is a common famine food. I'll as happily avoid doing so, as chronic cyanide poisoning is a problem in those areas during times of famine. Google "Konzo" for more information.
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