Comments by "Wide Awake Human" (@WideAwakeHuman) on "American Thought Leaders - The Epoch Times" channel.

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  4.  @Fastbikkel  Who are you? A Gilead rep? Honestly, the only 'unconstructive' part was you telling him that his comment was unconstructive because he used the term Big Pharma. I've worked in the pharmacy industry for nearly a decade and have heard everyone from pharmacists to drug reps to pharma execs and insurance employees use the phrase Big Pharma. You acted as if he had used some sort of horrible racial slur - instead your attempt to virtue signal just made you look very ignorant. Also, you do realize that Big Pharma spends more than almost any other industry on paying off members of Congress right? And you do realize that Gilead, the maker of remdesivir, used about $70M in taxpayer money to help develop the drug and then charges the American people over $3000/treatment in the middle of a freaking pandemic where people are dying? You do realize how oddly convenient it was that Gilead had spent time and money (some of it taxpayer money as usual) making remdesivir for Ebola but that was a bust - until poof, now it's effective against COVID, but the only way to make sure they can sell a bunch of it and make that loss turn into a profit is to make sure it's the ONLY drug that's effective and convince the US govt to purchase 500k doses at $2500/ea - bam, they made all their money back AND made a profit all during a pandemic. Never mind that HCQ is most likely more effective, since it's been shown to reduce actual mortality by up to 50%, has tons of anecdotal reports of being very effective although you wouldn't know it because that information has been censored mercilessly, costs nearly nothing and is a generic so pharma companies don't have the ability to price gouge like they do with remdesivir. THAT is the kind of thing that started the phrase BIG PHARMA and why using that phrase is perfectly acceptable.
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  9.  @justinchapman5876  Actually that statement about monotherapy being used to test for effectiveness is inaccurate, but you seem like a smart guy so let's see if we can have a productive back and forth.. Monotherapy is used to assess SAFETY, not necessarily effectiveness. Two very different things that are usually tested at different times when a drug is going through an initial approval. Safety in healthy people and then effectiveness in people with the disease that's being treated. We know the drug is safe from the millions of people that have been taking it for the last few decades. Everyone (almost) that's using HCQ for COVID have have been combining with zinc and vit D - that is what has been anecdotally very effective so that's what should be tested. There are many examples of this principle of synergism in antibiotics and chemotherapeutic drugs specifically - such as monotherapy with Vancomycin may not be effective against some MRSA strains BUT if you add an aminoglycoside then it works great.... so testing effectiveness of Vanc by itself for that indication is a waste of time because it needs adjunct therapy to work - synergism. This appears to be exactly the case with HCQ - it needs to be in combination with zinc at a minimum, preferrably with Vit D/C and inhaled steroid. The other real problem is the fact that somehow a drug has been politicized, which means you literally can't trust the people that you're supposed to trust - Lancet published a study which shows that HCQ actually causes worse outcomes than placebo - this study, which they actually published, was then retracted when REAL scientists started looking at the study and immediately found major statistical flaws. To be published it was supposed to have been vetted and peer-reviewed, that's the entire point of having scientific journals. The lead author was working at a hospital that had major financial conflicts where they were getting money from Gliead - the drug company making one of the vaccines. The authors also refused to release their raw data - most likely because it didn't exist, but either way this is a huge red flag.. But my point is that there is obviously an agenda within a large part of the medical community and that agenda is not saving lives - so just saying the BJM/NEJM have made a statement means nothing at this point - So I personally looked over many of the studies and I don't mean just read the abstract so it takes a lot of time - there is an overwhelming amount of evidence that the drug, when used in combo with zinc vit D works very well as long as it's used EARLY. In the middle of a pandemic when people are dying every day - this is the time to use the BEST option we have not to sit and wait for some "conclusive" evidence after a year long trial and the HCQ combo is very obviously the best option. Medicine is ALWAYS a measurement of risk vs benefit and rarely are there conclusive answers to most complex medical issues - the potential benefit very clearly outweighs the potential harm from 5-10 days of the HCQ therapy. Again, the PrEP and PEP stuff is also inconclusive - but of course it is, this thing just popped up a few months ago. It's still the best we have by far. I would be less inclined to use it as prophylaxis since the potential reward may be zero - but it should absolutely be given to nearly every symptomatic patient as close to onset as possible - If you'll read through those studies you'll see a reduction in mortality from 13% all the way to 50% - those are studies that didn't have to be retracted for being fraudulent
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  15.  @justinchapman5876  Oh I capiltalize random words in my head and it comes out on the keyboard sometimes.. .lol.. just disegard. On monotherapy - Sometimes a drug is only effective for a given indication when it's combined with another synergistic drug. (like one antibiotic will poke holes in a cell membrane and the other antibiotic can then enter a cell and destroy it - but alone they are ineffective) In those cases, testing the drugs separately tells you nothing about efficacy, because they need each other to work.. that's what I meant about mono testing sometimes telling u nothing about efficacy. HCQ needs zinc to be more effective. We have social media deleting videos and posts of actual doctors treating real people with HCQ/zinc so that the information doesn't get out - we have non-doctor politicians banning the prescribing of the drug for COVID as if that's even their right to do that - we have some boards of pharmacy trying to ban the dispensing of it - we have talking heads on TV talking about how it will kill you if you take it, which is demonstrably a lie - it's most definitely become political and many people and organizations are in on it. The only conclusion I came to about BJM/NEJM is that I don't trust any of their "statements" anymore unless I see the facts and they did nothing but make a statement. After a decade of reading and interpreting scientific papers, I'm much more inclined to trust the conclusions of 60 separate entities that did independent research all over the world simultaneously with hundreds of different funding sources and then reported those results so I can see them for myself. Rather than trusting some "statement" from another journal. Heck the USDA still recommends that people get plenty of whole grains in their diet - but science and the real world says that diets containing zero grains are better in nearly every single case. Do I trust the organization's statement or the data? Data every time. Again, you say that maybe more evidence will come out - but we're in the middle of about 700k people dying and there isn't time to waste doing a 62nd or 63rd study to show that it's effective when we already have this amount of data that show it works. Hydroxycholoroquine currently has 5 other off-label uses in the US.. (excluding COVID). So there are five things we commonly use this drug for that it's never been approved for.... some of them only have a couple of studies backing up that off label use, but doctors and patients still decide to use it because they think the benefit will likely out weigh the risk of this drug that is basically innocuous when used in short regimens like for COVID. The fact that it's not approved and has no year long RCT showing it's 90% effective are irrelevant at this point in time - patients need treatment now and we have something that will most likely help with extremely little risk of harm. If your grandmother had symptomatic COVID and the doctor offered her 2 choices: go home and take HCQ/zinc/vit D and there's a decent chance it will work but no guarantee.... OR just go home and take nothing and if it gets worse go to the hospital and likely end up on a ventilator... which one would you choose? Keep in mind there are hundreds of thousands of elderly people on HCQ for various diseases in the US every year (and millions around the world) that have little to no issues with it until they've been on it long term.. It's safe. It's most likely effective in a good number of people, especially when given early. And people are dying right now. If this was anything else no one would even question it - it would be standard of care at this point.
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  16.  @justinchapman5876  it's really simple, monotherapy only tests efficacy when it's used as monotherapy and no one is suggesting using it like that so those studies are irrelevant.... If the effect is seen in combination then the tests have to be done using the combination. And there is no "synergism" between azithromycin and HCQ, the azith is just there to prevent secondary bacterial pneumonia. The synergism is between zinc and HCQ and I've seen no evidence proving that doesn't occur so provide some if you have it. HCQ has a very low risk of seizures in a small population, no one is acting like it's a benign drug. Like I said all of medicine is a risk:benefit ratio. Every drug has risks but those risks are acceptable depending on the benefit the drug may deliver. But COVID has a risk of death, especially in some populations so the acceptable risk for adverse effects is higher than if you were treating arthritis... Which millions of people take HCQ for successfully... I'm very well aware of the adverse effects of HCQ having personally dispensed it hundreds of times and having multiple current patients on it. The zinc ur family member took most likely helped attack the virus somewhat, the dex helped with the inflammation. HCQ given at the same time would've allowed the zinc to work much better and likely reduced the severity and length of disease. U nitpicked about the number of studies... I'm not worried if there are 49 or 61 or whatever. 12 of 14 studies were positive... That's excellent. Do you realize that tons of drugs we use every day have studies showing horrible side effects and questionable effectiveness? Have done any research on what is considered normal before we use drugs off label? Again, people are dying now and the majority of the available evidence says this treatment works. Screen people for existing QT intervals, seizure history and retinopathy and use cautiously in those people. Otherwise it should be used early and often in pretty much everyone. Also, I'm not saying that individual studies can't be manipulated. But scientific studies have to make sense and if they don't then that comes out... I've seen no one bringing up inconsistencies in these studies other than ones that were faked to show it didn't work.
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  17.  @justinchapman5876  I'm not sure about your background or education level when it comes to scientific studies, pharmacclogy, etc so I mean no disrespect - but this is really an issue of facts - if a drug isn't effective alone then testing it alone will show that it's ineffective. If another drug makes the combination effective then the tests showing they are each ineffective alone are irrelevant and wouldn't lead anyone to believe anything other than the drugs alone have no efficacy - it says absolutely nothing about effictiveness of the combo. Yes, please look through the studies using the combo and given in early treatment - they're nearly universally positive - that was always the way it was supposed to be given, from the very first Docs (like Zelenko). The proposed mechanism of action makes total sense that early treatment would be the most effective - since once the viral load is very high and inflammation starts in the lung tissue then very little is going to be effective, mechanical ventilation just made things worse since you can't overcome an inability to exchange gas in the lung with a vent.. The evidence is very clearly in favor of this being a first line treatment while other studies are on going and while we have nothing better and while people are dying in front of us - at the very least we could've saved thousands of people had politicians not been banning the drug and instead made all the available studies readily accessible so doctors and patients could research and judge for themselves. Instead there has been a concerted effort from politicians, to social media, to supposedly legit orgs like Lancet to censor any information showing HCQ may be helpful and that's the real crime in this whole thing (other than the origin of the virus itself).
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  19.  @justinchapman5876  haha yeah pretty close - I've had kidney stones half my life... they suck and modern medicine knows nothing about what actually causes them so I've done my own research and gotten pretty decent at preventing them. Just part of life, it could always be worse. Thanks for the well wishes. Not an MD - actually a Pharm.D. - clinical pharmacist. I spend all day answering questions from doctors that need a drug expert that knows more about drugs and treating diseases than they do. So reading and interpreting clinical studies is a daily thing, knowing how drugs work, safety, mechanism, etc, is my wheelhouse. The mechanism of the HCQ / zinc synergism is most likely more complex than we know at this point (much like most drugs) - some proposed mechanisms include HCQ changing the pH of cells that make it an uninhabitable environment for the virus. Zinc has been studied extensively and is known to have some anti-viral properties by itself (that's why they make zinc lozenges for the common cold), even though the mechanisms aren't entirely clear. Adding HCQ and zinc together appears to have a synergistic effects, which just means they attack the virus from two different directions (via changing the pH and via a receptor that zinc works on) and have an exponential effect where 1+1 actually = 3. So if you change the pH it possibly makes the virus more susceptible to the zinc attacking it - making the combo more effective than the two drugs simply added together. Of course all this is theory on the MOA part, but the evidence is there. But there are several drugs that are on the market where we actually aren't 100% sure how they work - but we know they work and we know they are safe (at least for the term of time we have tested...lol) and we don't have to be 100% sure about how they work as long as they work and don't cause obvious harm. The body is so much more complex than most people realize. We're constantly learning new things about drugs that are decades old. But the data that HCQ and zinc and Vit D is effective is just irrefutable at this point, especially when we have people dying right now - and yet the media refuses to cover it. Social media giants censor anything trying to spread the information. Medical and Pharmacy boards are banning it or threatening to come after licensed professionals that dare to prescribe what they think is best for their patients. It's a travesty. In fact, I think it's the largest scandal of this entire thing that barely anyone is talking about. We have an effective treatment and yet we're destroying businesses, causing suicides to skyrocket and ruining lives because those in control of information are telling us we can't go back to normal until there is a vaccine. It's like there is absolutely no consideration for what this lockdown is doing to real people - depression, losing jobs, losing businesses, losing savings.. those are real effects that hurt real people. And unfortunately, people like you that are interested in the truth rather than just blindly defending what they hear on the news are like 1 in 1,000,000. Honestly, my heart breaks for all the people that are getting sent home or sent back to the nursing home to get worse and die alone all because it's politically incorrect to treat them with an effective drug because a President that half the country doesn't like said it MIGHT be a game changer months ago. I've read the studies and can't some up with another single reason why everyone isn't using this as a first line treatment - there isn't any actual science saying that it's dangerous. There isn't any actual science saying we have a better option at this point in time.. I've actually given 2 different prescribers (one MD and one nurse prac) all the studies that convinced them to start using it - they admitted the only reason they hadn't been prescribing it was because they had heard medical and nursing boards were actively watching for and attacking people who prescribed it so they just didn't to it for fear of losing their license and livelihoods. My grandmother actually texted me a while back and said she was going to stop taking her HCQ (she takes it for rheumatoid arthritis) because she heard on the news that it was a dangerous drug. She finally started taking it again when she couldn't get out of bed she hurt so bad. No one talks about all the people that were getting told their medicine is killing them by dishonest non-medical professionals on TV, but it has real effects.
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  22.  @magicman322  You're obviously totally ignorant about how and why drugs get approved for certain uses, what Trump has or hasn't done and who I am. First - there are NO drugs approved for COVID because it's a new virus - so of course HCQ isn't approved. But it works, so it should be used instead of letting people die for 18 months until Fauci's vaccine is ready that will likely have a 50% effective rate or less. Second - The only reason a drug gets approved for a specific indication is if a drug company spends enough money to make that happen - NO ONE is going to pay to have that done for a generic drug like HCQ that they can't make money on. So effectiveness and having an indication are NOT the same thing. Third - tens of millions of drugs are used OFF LABEL in the US every year - that means that drugs are used every day for things that they aren't "indicated" for because they'\re effective but no one paid to have that indication added to the package insert. So HCQ being for lupus and malaria have exactly jack sh!t to do with it's effectiveness in COVID. Fourth - Safety and effectiveness are proven for each indication - SAFETY of the drug was proven decades ago. Fauci HIMSELF was involved in a study in 2005 showing chloroquine (the more toxic version that we don't even use in the US) was effective at killing Sars-COV. FAUCI KNOWS that it works, but there is too much money to be made on a vaccine that his boy Gates is pushing. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/ - there's the actual journal article if you have enough brain cells to read and understand it. It's irrefutable. You can call me a liar and give no evidence and just spew hate or you can open your eyes and accept the fact that you've been lied to. Lastly - https://c19study.com/ - obviously you didn't go to this site and read a single study - or look at the fact that countries that started using HCQ EARLY have a fraction of the deaths per million that the US and other countries that refused to use it have. Please... explain all that away as a "lie." Next - go to med school or pharmacy school (like I did) - read the REAL science (like I did) and talk to REAL doctors (like I did) and then come back and chat because you're just parroting lies you heard on cable news and from your Lefty echo chamber and you sound ridiculous.
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