Comments by "Wide Awake Human" (@WideAwakeHuman) on "American Thought Leaders - The Epoch Times"
channel.
-
17
-
14
-
9
-
@Fastbikkel Who are you? A Gilead rep? Honestly, the only 'unconstructive' part was you telling him that his comment was unconstructive because he used the term Big Pharma. I've worked in the pharmacy industry for nearly a decade and have heard everyone from pharmacists to drug reps to pharma execs and insurance employees use the phrase Big Pharma. You acted as if he had used some sort of horrible racial slur - instead your attempt to virtue signal just made you look very ignorant. Also, you do realize that Big Pharma spends more than almost any other industry on paying off members of Congress right? And you do realize that Gilead, the maker of remdesivir, used about $70M in taxpayer money to help develop the drug and then charges the American people over $3000/treatment in the middle of a freaking pandemic where people are dying? You do realize how oddly convenient it was that Gilead had spent time and money (some of it taxpayer money as usual) making remdesivir for Ebola but that was a bust - until poof, now it's effective against COVID, but the only way to make sure they can sell a bunch of it and make that loss turn into a profit is to make sure it's the ONLY drug that's effective and convince the US govt to purchase 500k doses at $2500/ea - bam, they made all their money back AND made a profit all during a pandemic. Never mind that HCQ is most likely more effective, since it's been shown to reduce actual mortality by up to 50%, has tons of anecdotal reports of being very effective although you wouldn't know it because that information has been censored mercilessly, costs nearly nothing and is a generic so pharma companies don't have the ability to price gouge like they do with remdesivir. THAT is the kind of thing that started the phrase BIG PHARMA and why using that phrase is perfectly acceptable.
7
-
6
-
5
-
4
-
2
-
@justinchapman5876 Actually that statement about monotherapy being used to test for effectiveness is inaccurate, but you seem like a smart guy so let's see if we can have a productive back and forth..
Monotherapy is used to assess SAFETY, not necessarily effectiveness. Two very different things that are usually tested at different times when a drug is going through an initial approval. Safety in healthy people and then effectiveness in people with the disease that's being treated. We know the drug is safe from the millions of people that have been taking it for the last few decades. Everyone (almost) that's using HCQ for COVID have have been combining with zinc and vit D - that is what has been anecdotally very effective so that's what should be tested. There are many examples of this principle of synergism in antibiotics and chemotherapeutic drugs specifically - such as monotherapy with Vancomycin may not be effective against some MRSA strains BUT if you add an aminoglycoside then it works great.... so testing effectiveness of Vanc by itself for that indication is a waste of time because it needs adjunct therapy to work - synergism. This appears to be exactly the case with HCQ - it needs to be in combination with zinc at a minimum, preferrably with Vit D/C and inhaled steroid.
The other real problem is the fact that somehow a drug has been politicized, which means you literally can't trust the people that you're supposed to trust - Lancet published a study which shows that HCQ actually causes worse outcomes than placebo - this study, which they actually published, was then retracted when REAL scientists started looking at the study and immediately found major statistical flaws. To be published it was supposed to have been vetted and peer-reviewed, that's the entire point of having scientific journals. The lead author was working at a hospital that had major financial conflicts where they were getting money from Gliead - the drug company making one of the vaccines. The authors also refused to release their raw data - most likely because it didn't exist, but either way this is a huge red flag.. But my point is that there is obviously an agenda within a large part of the medical community and that agenda is not saving lives - so just saying the BJM/NEJM have made a statement means nothing at this point - So I personally looked over many of the studies and I don't mean just read the abstract so it takes a lot of time - there is an overwhelming amount of evidence that the drug, when used in combo with zinc vit D works very well as long as it's used EARLY. In the middle of a pandemic when people are dying every day - this is the time to use the BEST option we have not to sit and wait for some "conclusive" evidence after a year long trial and the HCQ combo is very obviously the best option.
Medicine is ALWAYS a measurement of risk vs benefit and rarely are there conclusive answers to most complex medical issues - the potential benefit very clearly outweighs the potential harm from 5-10 days of the HCQ therapy. Again, the PrEP and PEP stuff is also inconclusive - but of course it is, this thing just popped up a few months ago. It's still the best we have by far. I would be less inclined to use it as prophylaxis since the potential reward may be zero - but it should absolutely be given to nearly every symptomatic patient as close to onset as possible - If you'll read through those studies you'll see a reduction in mortality from 13% all the way to 50% - those are studies that didn't have to be retracted for being fraudulent
2
-
2
-
2
-
1
-
1
-
1
-
1
-
1
-
1
-
1
-
@justinchapman5876 haha yeah pretty close - I've had kidney stones half my life... they suck and modern medicine knows nothing about what actually causes them so I've done my own research and gotten pretty decent at preventing them. Just part of life, it could always be worse. Thanks for the well wishes.
Not an MD - actually a Pharm.D. - clinical pharmacist. I spend all day answering questions from doctors that need a drug expert that knows more about drugs and treating diseases than they do. So reading and interpreting clinical studies is a daily thing, knowing how drugs work, safety, mechanism, etc, is my wheelhouse.
The mechanism of the HCQ / zinc synergism is most likely more complex than we know at this point (much like most drugs) - some proposed mechanisms include HCQ changing the pH of cells that make it an uninhabitable environment for the virus. Zinc has been studied extensively and is known to have some anti-viral properties by itself (that's why they make zinc lozenges for the common cold), even though the mechanisms aren't entirely clear. Adding HCQ and zinc together appears to have a synergistic effects, which just means they attack the virus from two different directions (via changing the pH and via a receptor that zinc works on) and have an exponential effect where 1+1 actually = 3. So if you change the pH it possibly makes the virus more susceptible to the zinc attacking it - making the combo more effective than the two drugs simply added together.
Of course all this is theory on the MOA part, but the evidence is there. But there are several drugs that are on the market where we actually aren't 100% sure how they work - but we know they work and we know they are safe (at least for the term of time we have tested...lol) and we don't have to be 100% sure about how they work as long as they work and don't cause obvious harm. The body is so much more complex than most people realize. We're constantly learning new things about drugs that are decades old.
But the data that HCQ and zinc and Vit D is effective is just irrefutable at this point, especially when we have people dying right now - and yet the media refuses to cover it. Social media giants censor anything trying to spread the information. Medical and Pharmacy boards are banning it or threatening to come after licensed professionals that dare to prescribe what they think is best for their patients.
It's a travesty. In fact, I think it's the largest scandal of this entire thing that barely anyone is talking about. We have an effective treatment and yet we're destroying businesses, causing suicides to skyrocket and ruining lives because those in control of information are telling us we can't go back to normal until there is a vaccine. It's like there is absolutely no consideration for what this lockdown is doing to real people - depression, losing jobs, losing businesses, losing savings.. those are real effects that hurt real people.
And unfortunately, people like you that are interested in the truth rather than just blindly defending what they hear on the news are like 1 in 1,000,000. Honestly, my heart breaks for all the people that are getting sent home or sent back to the nursing home to get worse and die alone all because it's politically incorrect to treat them with an effective drug because a President that half the country doesn't like said it MIGHT be a game changer months ago. I've read the studies and can't some up with another single reason why everyone isn't using this as a first line treatment - there isn't any actual science saying that it's dangerous. There isn't any actual science saying we have a better option at this point in time.. I've actually given 2 different prescribers (one MD and one nurse prac) all the studies that convinced them to start using it - they admitted the only reason they hadn't been prescribing it was because they had heard medical and nursing boards were actively watching for and attacking people who prescribed it so they just didn't to it for fear of losing their license and livelihoods. My grandmother actually texted me a while back and said she was going to stop taking her HCQ (she takes it for rheumatoid arthritis) because she heard on the news that it was a dangerous drug. She finally started taking it again when she couldn't get out of bed she hurt so bad. No one talks about all the people that were getting told their medicine is killing them by dishonest non-medical professionals on TV, but it has real effects.
1
-
1
-
1
-
1