Comments by "SterileNeutrino" (@SterileNeutrino) on "2024 White clot quantitative results" video.
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ChatGPT proposes:
Potential Analytical Methods for "White Clots"
Histological Examination:
Thin sections of the clot can be stained (e.g., H&E staining) to observe cellular composition and structural organization.
This would differentiate between antemortem thrombi and postmortem clots based on layering, attachment characteristics, and cellular elements.
Mass Spectrometry:
Advanced proteomic analysis could identify the specific proteins present, potentially revealing unusual fibrin or platelet aggregates or even foreign material.
Scanning Electron Microscopy (SEM):
This would allow visualization of the microstructure, revealing whether these clots consist of abnormal fibrin matrices, contaminants, or other elements.
Fourier Transform Infrared (FTIR) Spectroscopy:
To detect chemical bonds and organic compounds, offering insights into unusual biochemical compositions.
Genomic or Pathogen Analysis:
PCR or sequencing could identify any viral or bacterial DNA/RNA, ensuring no infectious agents are involved.
Tissue-Specific Immunohistochemistry:
Detecting specific markers like fibrinogen, D-dimer, or immune complexes, which would indicate if these clots formed due to inflammation, autoimmunity, or vascular damage.
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