Comments by "Stephen Villano" (@spvillano) on "Chubbyemu"
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Well, whenever you're feeling more comfortable about life, remember, potato, tomato, eggplant, tobacco are all members of the nightshade family and well, toxic in their own special ways. Belladonna being another member, producing atropine.
Interestingly, some wild potato cultivars are being experimented with as a food staple, researchers using varieties originally grown by Native Americans. They're low in the known toxins from potatoes, but their native toxin is fairly low and in much lower concentrations. The toxin, tomatine is also present in tomato plants.
Nasty, nasty plants! I think I'll eat some tonight, just out of spite. OK, they're tasty staples, when properly stored and prepared.
I just keep thinking that, as I keep forgetting about the small eggplant in the fridge... I make a kick ass eggplant lasagna with homemade tomato sauce.
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I do rotate my foods literally daily, as I honestly can't comprehend eating the same thing every day.
I also hadn't salted my foods in decades, as there's plenty of salt in things like canned vegetables and that's worked well for me for decades.
I did however, despite ample sources, chronically run low in magnesium. Mystifying, but a supplement helped when it dropped extremely low - once doctor actually followed his treatment plan.
Then, four months of continuous or nearly continuous diarrhea arrived for an extended visit. Bristol 6 -7. Doctor was a bit distracted with some other issues that could do that killing me thing, so overlooked the overloo complaint for a couple of months until I reinforced the complaint a bit more strenuously and blood work came back with a severe sodium and chloride ion deficiency, as in I should've had severe cramping and possibly some entertaining cardiac conduction issues.
GI consult it is! After a number of entertaining misadventures resulting in missed colonoscopy appointments, largely involving a rather comedic number of transportation issues of the most improbable, crap for luck sorts, this appointment stuck. Crohn's and of course, erosion right were salts are scavenged.
On a biologic now, last induction dose is just shy of two weeks from now. We'll see if that's effective, as there was some annoyances with what the GI specialist wanted to utilize and what the insurance company has a warm and fuzzy with and for once, due to efficacy rates, I rather agreed with the insurance company.
They did check for some micronutrients and folate and B-12, both star spangled happy mid scale.
I've identified one flare trigger, <grumble> <grumble> <grumble> chili peppers. Love them, but the neighborhood around my ileocecal valve really wants to run that stuff out of town.
And for entertainment's sake, my endocrinologist informed me (well, the blood tests did as well before my appointment) that my body got bored with Graves' disease and instead is visiting Dr Hashimoto.
And if one couldn't take a guess from the maladies, yeah, I'm a desiccated smoker. OK, my hydration is fine.
But, given those issues and their linkage and some lumbar issues that'll likely require surgery or my switching to permanently seated and needing a diaper, yeah, think it's time to toss one bad habituation. So, the sex swing goes!
OK, the smokes gotta go.
Never got that other thing, as neither my wife or I had a yen for being in traction.
One needs to retain one's sense of humor and my ancient EMS humor remains alive, imbalanced and unwell. ;)
And at least my herbal teas are well tolerated - drank not for some medicinal value, but because they just taste so damned good. Favorites being artichoke tea, ginger-tumeric and hibiscus. Might try some rose hips, if I can clip some when the Rabbi next door isn't looking... ;)
And note to self, discuss with doctor some forearm novel behavior, sudden 5 - 6 cm inflammation and intense itching, with sub-centimeter hives that hemorrhage and resolve in about a week, a bit longer than my usual healing time and I clot quickly, as observed in bleeding time measurements and when using the glucometer due to the steroid I'm briefly saddled with. Was just finally clocking at pre-diabetic at age 63, in a family where diabetes is usually diagnosed in the age 30 - 40 range and dialysis is needed by age 50 - 55 ("It's in the genes, why fight it" being their mantra and mine being, over 28 years in the Army, fighting's what I'm best at and loathe).
Shit. Forgot to pick up coffee when I was at the store, gotta dip into my pantry reserves, as a winter storm is coming. Probably revenge from Canada for those tariffs... ;)
That's OK, I pre-pre-retaliated by buying 2.5 gallons of Canadian canola oil.
But, the good news is, eggs in the US should be coming down in price, given one certain POTUS incessantly laying eggs...
I'll just get my coat on the way out...
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While there are risks within even a high therapeutic dosage level with diphenhydramine, it remains my antihistamine of choice, due to its slightly higher efficacy level and being common in our military drug chests. When it's not quite effective, one can rapidly follow with dexamethasone or other steroid and of course, to close those leaky, dilated vessels, good old epi, followed with a rapid MEDEVAC.
Once, I lost the advantage of rapid evacuation and got saddled with severe anaphylaxis, secondary to longstanding beesting allergy and several stings. Yeah, that man kept me busier than a one armed paper hanger! Used up a fair number of drugs in a kit designed to supply stabilizing care for 1200 men. Our surgeon was supervising and only offered a sparse few suggestions of odd one off uses of some drugs, after he noticed that I was calling out using Promethazine for its antihistaminic properties, synergising it with an analgesic to ensure that the patient not injure himself. It also meant that I was beginning to scrape bottom in the drug kit and my knowledge base and doctor suggested a few drugs, even adding atropine to counter the recalcitrant bradycardia.
Learned a few things from that, mostly, on how to more politely indicate outrage over unnecessary delays in MEDEVAC requests, some of which made it up to division level as the most polite alternative usage of terms that otherwise would be translated far more profanely.
Worst twelve hours of my life! But, he finally stabilized, was hospitalized anyway, as I wasn't having a warm and fuzzy over the encyclopedia of drugs utilized to stabilize him.
Suffice it to say, the surgeon gave due credit, which I honestly didn't give a damn about and had some interesting words to say to command over unnecessary delay of evacuation of a critical patient during a training exercise. He also had a touch of ethanol, for medicinal purposes that he prescribed a strong dose of for both of us. Largely, as we both wanted to hit a specific individual over the head with a flung M1 Abrams tank.
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@HO1ySh33t except for that whole chlorine being neutralized and removed from the water plant's output.
Used to do water purification as part of my military job. The only place one could find any chlorine residual was in field water supplies, where free chlorine at 10 times the level allowed in a swimming pool was required to prevent water borne illnesses.
And those nitrates are present naturally in many meats without any curing, that whole proteins being lousy with nitrogen and 80% of our atmosphere being nitrogen. So, if you're still upset about that fact, maybe your family should've stayed on the battlestar.
Because, in the end, Paracelsus got the right of it. The dose makes the poison. Pure oxygen is ungodly poisonous. Too much water is poisonous. Too much salt or potassium salts, poisonous. An absence of any of those, also absolutely lethal. Phosphorus, totally lethal, right? Try making a cell membrane, DNA or a bone without it. Calcium, really nasty element by itself, it'll literally burn you. Can't move a muscle - literally, without it. Used in all manner of high energy processes that sodium-potassium lack enough energy for.
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@johnmcclane4430 not that will unbind nicotine. Pralidoxime works for organophosphorus toxins, such as insecticides and nerve agents, but is ineffective against nicotine, as it can't bind with nicotine. Atropine can counter some of the symptoms, benzodiazepines can help with the seizures, but still can't unbind the receptors. Add in excitotoxicity and lowered oxygen, wreaking havoc in the cellular respiration chain, well, humans can be fairly evil with chemistry, but nowhere as evil as plants can. Plants have a 700 million years of practice on humanity and excel at chemical warfare between one another and animals.
It is a bit two way, as the use of nicotine recreationally, as well as a number of other phytochemicals prove and well, many of our spices either work as antimicrobials on foods or work as antiparasitics in our GI tract, as well as make foods taste good. ;)
And of course, some phytochemicals are medicinal, atropine originating from belladonna, as one appropriate example. Nicotine being present not only in tobacco leaves, but also in tomatoes, aubergines and potatoes leaves in much lower content and with other toxins to discourage herbivores from consuming them.
Worse, even dialysis or similar filtration is ineffective at removing nicotine from the blood, it's downright pernicious.
Note, I didn't go into phytochemicals commonly abused for good reason.
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@a.deadgirl I dunno, I'm more of a function over form guy myself, so what someone or something looks like isn't as relevant as what someone or something operates like.
So, that my physician at the hospital having body builder muscles wasn't of relevance to me, that she had a clue how to keep the treatment team of cardiologist, pneumonologist and endocrinologist working together to get me breathing well again was the priority, not hair style or lifting technique (actually, the muscle build is more of an orthopedic surgeon's build). Went in breathing around 60 breaths per minute, due to mild pneumonia, left stable, breathing room air comfortably and while still dropping weight, now I'm dropping about a pound per week, rather than ten pounds per week and that'll taper off as the thyroid is wrangled the rest of the way under control.
Just as well from my seat, as I dealt with plumbing, structural and infectious diseases in my military career, dealing with things that aren't plumbing was and remains well above my pay grade.
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I was just mentioning Dr Karen Wetterhahn in another comment. At the time, it was presumed that the latex gloves she wore would be effective protection and alas, they were not.
Two compounds are pretty much the penultimate in evil, dimethylmercury and chlorine trifluoride. I'll happily work and play with either or both, as long as they remain on a different continent than I am.
The one, even a single drop is lethal for, the other is so much better an oxidizer than oxygen is, it'll not only burn ashes, it'll burn glass, sand, concrete, water and any soul coming into contact with it.
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Outbreak in Florida from spas and "botox parties", apparently, the "botox is tainted", which given the symptoms, likely is illegally imported bootleg botox that was massively underdiluted.
Meanwhile, I've taken to canning vegetables in half pint jars for individual servings, as the small packages are priced nearly the same as a full sized can and a full sized can would be wasted. But, knowing the bacterial conditions, I use a pressure cooker to prepare the jarred veggies and well, double the pressure cooking time to ensure full sanitization, then monitor a the lot, if one fails out of a batch, I'll be waiting and watching closely, if two or more fail, the lot is getting tossed, the jars and lids blasted in the pressure cooker after bleaching, then reused.
If I'm to be paralyzed, it'll be from paralytic shellfish poisoning and given how far inland that I am, that just isn't gonna happen. ;)
Although, I have enjoyed some potatoes that started to green, I removed the slightly greened sections and toss the rest as they soften and toxins are accumulating.
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Garlic and ginger are highly effective!!!
At making some food dishes extremely tasty.
In high concentrations, such as in dry cured meats, they'll act as antimicrobial, as microbes can't metabolize them and our metabolism, due to our immense liver will, neutralize them. Some, like hot peppers can even stun parasitic worms, but we have drugs that'll eliminate all, rather than stun some.
So, spices for taste, oils because they smell pretty (they smell like nothing to me, I have no sense of smell, taste is taste bud driven for me), tea for its flavor or as a stimulant.
I'll go with coffee or, when foggy, ginseng, your mileage will vary.
And saffron tea, because it's delicious!
I'll sugar and milk coffee, teas are drank neat, for their own flavors.
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Well, quite a few spices do have antibiotic properties - in food. Before refrigeration, spicing and drying were the only realistic ways to preserve food.
But, food doesn't have what we have, a digestive system, which dismantles most of what we eat to chemicals that we need to survive, so those spice antibiotics get digested along with the foods that they made taste yummy.
As for alcohol, good in moderation for recreation, decent sanitizer for 60% or higher (95%, not so much due to surface tension and some chemical issues that also make it lousy for extracting spices), as is a quarter cup of household bleach in a gallon of water (just don't leave it sitting around, it'll slowly degrade to uselessness), that doesn't mean one should drink any to prevent illness, as doctor mentioned.
But, a bit of ethanol can take the edge off of irritability when hearing and reading a lot of the nonsense being promulgated as magical cures that simply won't work or worse, can injure or kill.
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Delivers said Karen to NASA's vacuum test chamber, locks her inside and activates the vacuum pump, saying "bon appetit!".
After all, the only thing that isn't chemicals is various forms of radiation, so she obviously wanted to consume absolutely nothing and I do aim to please.
RSFAKQJ10 RSF, that's hydroxic acid to you, bub! ;)
Or hydrogen hydroxide, since it's both an acid and base, save where it isn't. :P
Jesus, I'm doing chemistry jokes and elsewhere, physics jokes, totally sound like a geek. Oh well, if knowledge is power, one should be a nuke. :D
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I've a rather narrow number of fungal species that I'll consume. In a fair part, due to allergies to things like straw mushrooms. Get even a bit of straw mushrooms in a meal, I'll be literally projectile vomiting.
Oddly, I can tolerate a number of other mushrooms, most of the brown mushrooms like portobello, shittaki, porcini mushrooms I can consume as much as I want. Go figure. But, different species, different proteins.
Fooling around with various toxic forms, thanks, but no thanks. If I'm not fond of taking prescribed drugs, I certainly am beyond leery of uncontrolled substances going into my body or on it or hell, even near me.
The only fungi I'll mess with under less controlled condition is yeast in my bread or perhaps, with some beverage and I've not made wine in decades.
Which reminded me, just added some portobellos to my shopping list. I'll be tossing some, well diced, into a lentil based "meatloaf" I've been experimenting with. My diet is omnivore, but I do enjoy a change of pace with my meals. Never could figure out how some folks could eat the same thing every single day!
Although tomorrow's meal will be to polish off a bit of leftover sauce, with additional sauce added to some of my thirstier noodles...
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@aperocknroll88 love them as a comfort food and for veggies, frequently as a soup and stew ingredient. The fish, well, a memory of when I was a boy scout, back during the ice age.
Annoying, the only realistic quantities are five gallon buckets, which is an absurd quantity for me, a gallon max would suffice for my needs for what is a rare guilty treat of a comfort food.
I can only find it at a reasonable price in five gallon or more prepper quantities and that just ain't gonna happen. No room for it and no need for such a waste, as I've absolutely no chance to wade through that much guilty pleasure without said pleasure becoming deleterious due to excess in favor of fresh food the rest of the time.
So, if they've got gallon and under quantities, I'll be interested, shoot along the URL, even here usually allows one quick link.
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There are two forms of water overdose. One is commonly referred to as drowning, freshwater is preferred for those treating that condition, as that will enter the bloodstream, rather than pool in the lungs and keep causing problems like seawater does.
The other is water intoxication. Got to work with one case, annoying and I'm glad that the idiot didn't go to such insane excess as this video's case did.
Dealt with more dehydration, electrolyte imbalance due to perspiration electrolyte loss.
But, a few service members did overindulge in water and entirely follow civilian population salt intake rules, resulting in hyponatremia and others refused to drink "water that smells like a swimming pool" (utter nonsense, as the residual chlorine level is ten times that of a swimming pool, for good reason, it's in water trailers left stewing in the sun and otherwise, would incubate all manner of microorganism that isn't preferable to imbibe a culture of).
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@juanbrits3002 actually, she was. You should always wash produce before consuming it, for just this reason. Hell, the Army not only washes produce, they disinfect it with calcium hypochlorite bath before using it, again, for just this reason.
Worse, she put the infectious lettuce on a burger, then left it to incubate for a day, as the meat makes for an ideal culture medium for e. coli.
Ironically, we naturally harbor one type of e. coli in our gut, the toxin seems to have originated in a bacteria that causes a type of dysentery, itself related to e. coli, but in this case, it's typically a strain common in livestock that were infected by a bacteriophage, a virus that only attacks specific bacteria species and strains that gives this type of e. coli the ability to make the toxin. The toxin going through cells endoplasmic recticulum, basically punching out critical sections and traveling on to keep doing so, rendering the cell incapable of making proteins.
Mother nature sure seems to take a great dislike of us at times!
I didn't know that shigella like toxin and shigella toxin behave so similarly to ricin, nasty stuff, as it hits so much of the cell's ER! Nasty stuff!
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@clydecraft5642 I've got two addictions, curtailing consumption causing PVCs enough to toy around with v-tach. Caffeine and nicotine.
Around the first peak of COVID-19 hospitalizations, I was hospitalized with a form of heart failure, caused by a thyroid storm. With the storm managed, I began to rapidly recover. About the point where I tried to sneak out for a smoke, well, the staff had a chuckle (one of my nurses literally caught me at the exit to the building as she was coming on shift, the nurse administrator having a jolly laugh over the whole thing) and knew I was pretty well recovered. Two days later, I was discharged.
As for soda, I prefer my water plain and might, just maybe, have one soda per day and usually, it's only once per week.
I do drink a lot less caffeine, primarily coffee, due to damage to one heart valve from, despite being vaccinated and boostered, COVID. I shudder to think what would've been damaged or destroyed without that vaccine to blunt the worst of the infection!
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@purupurupikopuyo-k5w I had unexplained diarrhea for four months, doctor initially being a bit distracted over some things that could quite literally kill me quite swiftly, what was initially characterized by a radiology resident as severe mitral regurgitation (it was low end moderate) and an abdominal aortic aneurysm, which is a big deal.
Once those were at mischief managed, aka watchful waiting, it was, "Hey wait, you said four months?! Let's order some tests now".
No eggs or worms or suspect critters like protozoa was the first test. Inflammatory markers were high. Sodium, chloride and magnesium were dangerously low. A few other markers were ambiguous for several conditions, which isn't unusual in such cases and I was referred to a GI specialist.
A few additional tests, primary prescribed a steroid to calm the raging brown waters, which controlled the worst, GI doctor prescribed a colonoscopy (which amazingly went through well, three other attempts leading to a comedy of events like broken down cars, a major storm rendering getting the procedure done, etc), which revealed Crohn's disease.
My primary, knowing my dietary habits of basically everything from scratch because I'm a cheap SOB, ordered me to eat prepared foods, an Rx for magnesium oxide and called a few days later to see how I was faring. I explained that I'd excavated my salt cellar and was salting my foods for the first time in over 30 years, repeat testing showed much better sodium levels, chloride levels were happy and magnesium was dead center of whatever normal is. Minimal processed foods, because well, they suck.
GI doctor also ordered a few metabolic and specific tests, B-12 was good, as was folate, which was surprising given the inflammation, eroded tissues and other deficiencies, so obviously my diet was more than sufficient.
Just got my second infusion of infliximab to curb some of the immune system effects that spur the wider inflammation, we'll see, it'll work, not work or I'll grow an ear from my scrotum. OK, I invented that last bit.
It'll work or we'll have to stop playing with TNF-alpha antibodies and go with vedolizumab, which is a bit lower in efficacy, but still fairly decently effective, but not very well liked by my insurance company. We'll see how it goes. I'd already staged things to appeal successfully if their recommended drug is ineffective and to put it simply, I agree with their medical reasoning in this case.
My knowledge of anatomy, physiology and pharmacology is quite good, so if it came to an argument, those physicians are going to have one hell of a tough row to hoe, as I've also written peer reviewed papers in other fields and know how to present an airtight presentation.
And high on my to-do list is smoking cessation, as I've also noticed before the biologic treatment some signs of autoimmune dysfunction that could be warnings of some things becoming a problem and autoimmune and autoinflammatory syndromes are worsened by cigarette smoking. And it's also likely I'll need surgery for a disc problem and that has a very high failure rate in smokers.
I know these things because Google scholar is one of my closer friends, as are peer reviewed papers on such subjects. And peers love little more than to savage shoddy work from a peer.
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Many years back, when some guy named Bill was POTUS, I was repeatedly and tiredly, asked, "What do you think about the President allowing gays to join the military"?
I didn't miss a beat and said, who said that they weren't there, we have a Navy, don't we?
That was actually honest, in some ways. Navy has a more congested culture, due to ship size and berthing, hence, there is a preference there and for their more famous Corps.
I won't even go into the Navy originated joke about submariners, where 100 men go down and 50 couples come up.
Real world, rather than joking. I've served with people who are pretty much every shade of the sexuality spectrum, they trusted their lives to my care, I trusted my life to their care.
Or, as I've joked, "I don't give a shit if they love viewing my (anatomical location omitted, due to variability), as long as they cover it, the same is true for them".
And that was before our current cocktail successes to halt viral progression.
Because, all military service members are potential blood donors. So, I have a choice of dead for not getting replacement of blood or not dead if I were wounded.
Until we can fix dead, no, not going to suggest a suicidal path by denial, save in terminal conditions and under fairly modest conditions.
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@anonjoeoof2113 I tend to not get injured, since retiring from the Army. Previously, when I did, I rarely needed hospitalization, save a couple of times for outpatient care. One advantage of being a medic is having one's own aid station that one works out of.
A couple of months back though, well, heart racing, BP insanely high, SPO2 of 85 and obviously feeling lousy - while COVID-19 was peaking in my county. You can guess what was running through my head. Pulse 135, BP 225/130, SPO2 85, atelectasis with fluid and partial collapse in both lungs, totally fun times. Noted also, even if doctor didn't mention it was phenomenally high voltages shown from the left ventricle, which told me longstanding hypertension to the point of cardiac muscle hypertrophy. Light bulb comes on - it wasn't COVID-19, it was proved out that essentially, my blood wasn't moving well from the tachycardia and rather narrow window in BP, resulting in lung dysfunction (there are a few other factors involved, it's a touch complex for here).
COVID-19 was indeed ruled out, although heparin was given to ensure no unpleasant surprises and dexamethasone administered for the inflammation, preventing some really degrading conditions. Free thyroid hormones were elevated over tenfold above normal, thyroid stimulating hormone was nearly absent and I had a previous diagnosis of Grave's Disease - a form of hyperthyroidism. I was in a classic thyroid storm, indeed, a fever can also be expected during a thyroid storm, but that remained absent.
So, the words that I never thought I'd utter came from my lips, to laughing agreement from doctor, "Oh, thank God, it's only a type of congestive heart failure!", rather than COVID-19, which would, within six sigma certainty, punch my ticket.
Used to be an SF medic, my A&P knowledge, as well as general medical knowledge is more than sufficient to converse comfortably with physicians, had to do that by radio on occasion for treatment suggestions within the scope of equipment vs time to evacuation to definitive care, with an eye toward stabilizing the patient for up to a day or two. Can't accomplish that in a knowledge vacuum. Drugs carried were those that, optimally would have multiple uses - even if used off label and critically, were temperature stable in an uncontrolled environment.
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