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mcozy333
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Comments by "mcozy333" (@mcozy333) on "JRE Clips" channel.
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Except com[paring shows this ==== LD50 alcohol = 10 to 1 ... LD50 cannabis = 40,000 to 1 ... cannabisd is 40 thousand times safer thn alcohol and should be mentioned and known by people
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@KTGMetalheadSwiftie Lethal Dose 50 . another way to describe = Therapeutic index ... this describes how safe a compound or substance is for treating severe disease without the compound or substance being a toxin in and of itself during said treatment . therapeutic index of cannabis is 40,000/50,000 to 1 ... not 4,000 . and alcohol too remains down @ 10 to 1 ... Aspirin ? 20 to 1 and last and the least of all = Chemotherapy = 1 to 1 ... chances of surviving that is about as low as it can possibly be.
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CANADA - a statistical analyses the next day after they """ legalized""" cannabis would show or prove sudden psychosis in relation to metabolizing that particular plant ... thousands of NEW people to ingest it all of a sudden would lead to certain and provable results and we could then say it causes psychosis ... ALAS,. no such thing has happened and we even have Colorado and Washington in the States to pull from ... no increase whatsoever in places that legalize the plant all of a sudden . some people feel uncomfortable in their body when cannabis plant metabolizes in the bod ... our comfort level is being challenged LOL
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do not use it
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second largest accumlation of cannabinoid receptors are located on reproductive cells ( organs ) ... the brain contains the most cannabinoid activity while the sex function is second ... then peripherally all metabolically active tissues contain cannabinoid receptors
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you will need to find some outdoor grown sativa. or find some brick weed from Mexico
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@petersmith1886 Sorry, thought you were in the States ... looks like you basically have the same thing going on there too though .... Good luck , stay safe and Enjoy!
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check out Russo' article on cannabis to help that condition = Taming THC
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Winner ! one plant one man
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@ThatCarGuy1983 all chordate life forms have cb receptors and an endocannabinoid system to make those receptors function ... all metabolically active tissue cells are endocannabinoid system ., predicted that 70 trillion cells make up the ECS !
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your liver does not metabolize 11 Hydroxy THC well... delta nine becomes 11 hydroxy THC in the live via First pass metabolism... this - after you eat a meal your liver is occupied for up to 45 minutes and will not handle first pass as well... ( hence why sugared desserts are not good, they make it passed first pass) ... you may could benefit-- eat a large meal and then proceed to eat your edible... this could allow it to make if past first pass somewhat ... another way I've seen work... eat edible before bedtime... metabolism slows to a crawl... most people when they awake feel effects when metabolism kicks in... this method of ingestion is recommended for early morning sickness where the person upchucks first thing in the morning but could also work for your issue as well
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cannabis helps people with schizophrenia as much as anyone else to ingest it ... maybe even more so and Especially certain varietal;s of the p;ant will be more beneficial to those people
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look into = clean air path dry herb vaporizers like the Solo and Fury Edge vapes ... you receive way more medication from a vape than smoking the plant
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the worst con is the attitude toward the plant and then that gets places onto man . if only man and plants could get along !!
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when the world has claimed fro close to 90 years it is bad for you and all the research performed shows with biochemistry how it is 100% good for you the benefits then matter in an extreme way ... as identified with sciences and denied by politicians who could give a fuck a bout that science
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CANADA - the next day after legalization and thousands of people who never tried cannabis have done so - a psychosis episode would have shown immediately on day two ... the news would have had that news posted everywhere , psychiatrists would have been up in arms ETC..... Alas, no such occurrence has happened anywhere at any point in time
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@unitedstatesirie7431 Ok, so show one viable provable case of someone going completely crazy form metabolizing cannabis lipids or maybe cannabis terpenes caused it ? try and identify in the plant what exactly can even cause such a condition in a man or person .... I'll await your finding right here when you are ready
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@unitedstatesirie7431 yeah, you l;ost me ... I do not speak in riddles ... what are you saying ? cure ? what cure?
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reallt the direct relation to it being a gateway is the underground scene that peddles the plant ... they peddle other substances as well and will gladly sell any to any person ... they do not card you ... cannabis dispensaries on the other hand eliminate a large portion of that as long as they are not dealing out the back door too... still though someone willing to ingest cannabis is deemed more willing to ingest other things as well so there is that. in newly legal States that have accepted cannabis more the teens are less drawn to using cannabis in any way as the illegal allure diminishes . the rebel ceases to have something to rebel against
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so far with biochemistry I have only been able to find supportive roles from the cannabis plant metabolites being metabolized in man /woman/child ... the actives in the plant are C-21/C-22 terpenophenolics ( lipids with terpene backbone) ... known as phytocannabinoids ... they are meroterpinoids and as such are an essential fatty acyl in our cells, similar to essential fatty acids ... this is advanced biochemistry that I've sifted trough to make these conclusions eTC.... even when smoked the cannabis medical compounds are in the smoke . there is so many better forms of ingestion with no smoke and then the medical aspect really takes off as you are not dealing with toxins from smoke to reach a medical effect ETC.... anyway , I'll link a few Anti-inflammatoryω-3 endocannabinoid epoxides https://www.pnas.org/content/pnas/114/30/E6034.full.pdf Interplay Between n-3 and n-6 Long-Chain Polyunsaturated Fatty Acids and the Endocannabinoid System in Brain Protection and Repair https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656721/
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@b3astlyify Endocannabinoid system is truly the most fascinating discovery I have found . the fact that each time I learn about it I know I am but a few people on the earth who even know this , while other people who would benefit otherwise are running scared , incapable of honest interaction, pulling from knowledge of psychopaths who have been running things the last 100 years or so . Tis why I only trust biochemistry ... no lies politicians sitting high and mighty dictating the health of the people based on their own agenda eTC... a few more links since you seem interested ( Models?) here is the largest source of info on the Net - grannystormcrowlist https://grannystormcrowslist.wordpress.com/ she is working on this years list too as we communicate here ... and here is a great Docotr and one of the only people ever to teach endocannabinoid system in a curricular setting http://canna-sapiens.com/ Edit - here is 28 ,000 results = https://pubmed.ncbi.nlm.nih.gov/?term=cannabinoid
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@goat2503 so Glad to help over this internet highways ... ther too are cannabimimetics which are cannabis type compounds found in other food stuffs ... a great one to focus on is whole peppercorn ... most people already have it available and do not realize how medical that is ... there is beta carophyllene ( BCP) in there that is a dietary cannabinoid . BCP is a selective agonist compound in cannabinoid type 2 receptors ... BCP has a 24 hour half life so really does help to direct cannabis plant metabolism better if you ingest BCP before cannabis ... the idea is to load cb2 with BCP and then the THC can better direct to cb1 ... you can slow cb1 effects of THC too via taking BCP after the fact ... taken before cannabis increases cb1 effects, taken after cannabis decreases cb1 effects Edit - there are way more cannabimimetics in the world too that we have available ... basically anything that is metabolically active in the endocannabinoid system
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@goat2503 there is a forum thread at grasscityforum - cannabis black pepper is the thread title ... you can find it in the medical section at that forum ... I'd link out but you will then probably miss the post as youtube deletes them
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so the active constituents found in Cannabis / Hemp metabolize into man to create neuronal plasticity in cell structures... the human bodies' cells synthetically make a form of cannabis type compound ( endocannabinoids) . those compounds are ligands that enter into cells and create neurotransmitter messaging. for cells to maintain cellular homeostasis and to form those signalling canna metabolites the cell cleaves Fat from its own phospholipid bi-layer and adds a few enzymes to that fat to crystallize a canabinoid receptor channel to channel the fat. Bio-active Fat ... bio-active lipid. phytocannabinoids from cannabis are bio-mimetics to endocannabinoids... the only difference = cells do not need to displace phosphatidylcholine / serine from their structure via cleavage when already formed phytocannabinopids metabolize through the pathways instead.
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there is not one provable case of someone going psychotic from metabolizing cannabis ... people act in certain ways when " under the influence) but as a professional has said - when you ingest cannabis you are not crazy you are High
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No not at all .. in fact metabolizing the plant activates areas in our bodies that are cancer preventative .. activation of the endocannabinoid system .. ECS is our cancer defense
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some people who are schizophrenic need cannabis plant . it can calm the most unsettled people ETC ... even more so certain types of the plant ( chemovar / cultivar / phenotype / chemotpyes ETC.....)
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any belief system we use to block us from reality causes severe psychotic issues in our mind frame ... just sitting there with no thoughts or opinions ( belief) is more real and true
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@tealatata I'm talking about - we are more than a belief system .. I agree with your og post, any belief system we hold onto limits us completely ... we cannot progress further than the belief itself and turn to other people who have opinions to make the belief system to begin with ... just sitting still and observing with no beliefs at all is more real and true
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go to pubmed and type in " cannabinoid" into the search box ... 28,000 + articles pop up ... our Government has failed us in this regard and no one is going to be able to Show him more than is available on our own Gov website ! if we need a reason to " legalize" cannabis then the medical facts should suffice however ther main theme of the US Gov is no medical value whatsoever ...
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even ingesting entire plant cannot provide enough to popison a person ... the THC metabolite is biologically available in man ... the cells in man use that type of lipid to make signaling connections in the cells . known as cannabinoid sciences / endocannabinoid system / lipid signaling
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marijuana is a tactical assault word ... not a viable plant species name , a Government pawn to shoot at wlll- the people
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if we were to suddenly discover cannabis plant dfor the first time today it would be heralded as the greatest plant discvery in the found world... and that could just be OG field hemp that was the first type of cannabis and not the sophisticated plants we are witnessing today... go ahead and jump ahead to now and compare to just OG CBD plains field hemp from 50 million years ago
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have you read Russo's article -= Taming THC ? great read on depression and cannabis
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@openpeace1174 people in fear are better controlled ... simple as that ... free people in Love =- out of control
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@donniebuza2597 you can show people like that all the research in the world and they completley ignore it
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Hemp Shrimp !
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may your land never be short on Leaf !
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also, with cannabinoid science of the endocannabinoid system we can prove cannabis is essential in our cells ... the lipids and terpenes are that ... the seed oil is loaded with essential fatty acids . the phytocannabinoids themselves are essential fatty acyls . check out the sciecne of cannabis and be amazed ... the only negative we can say about it si that it can be smoked ... so can car tires so there is that
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@mathiuseden9605 yeah , ther are huge differences in the plant depending where it is from on the earth ... people like that guy would be the last to care of that though , hence my response
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the only actual proof we have of what metabolizing that particular plant does to us is an increase in plasticity in our cells ... the actives in cannabis are PUFAs , our brains are 50% PUFAS/ HUFAs
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our sickness is other peoples' Gain ... the sicker we are the Better
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that stuff is a COX block, that is how it works however blocking COX ( cyclooxygenases) creates issues ... cannabis actually supports COX function and does not block it hence why it cannot harm those pathways or effect them in such a way as to close them down completely
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to many people believing in a certain way will not let up on that thought process andf just let it go ... a way of saving face ETC ... and not have everyone around the tell them I told you so ETC ... basically living with head down in a sand pile and only hearing their opwn thoughts as they bounce around all the time with no new info to pull from ...
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it has been tested in other countries... US GOV paid Israel 150k a year since 1964 to research cannabis while research in America has been smoke only testing allowed... and patents on cannabinoids,... that is the kicker ... we are behind the scenes quietly patenting cannabis compounds " for medical use!!!!) while the real plant remains illegl
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Pharma is replicating the compounds therein ... marinol / dronabinol / cesamet / syndros / rimonbrant / nabilone = all cannabis replicated pharma synthetic drugs
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here is the Research that the Shaffer commission found = 1974 Virginia medical school proves cannabinoids kill cancers https://duckduckgo.com/?t=ffcm&q=1974+Virginia+medical+school+proves+cannabinoids+kill+cancers&atb=v165-1&ia=web
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banning the beneficial plant in the first place was the psychosis ... Surgeon general of the time ( 1937) claimed that smoking the plant will make 6 inch fangs grow dripping with blood !!!!! I mean people paid attention to that and took note , some people actually believed that was a possible scenario .. they went on the make the Reefer madness doc
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CBN ( cannabinol ) is oxidized THC. CBN is the sleep aid compound in cannabis , even better than CBD for a sleep aid
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when asking religious people certain questions especially around personal freedom to know God, all kinds of blocks go up and primal fear of teh unknown racks them
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